| Protein ▾ |
UniProtID |
Domain |
Species |
Description |
Publication |
Save |
View |
| Aft1 |
P22149 |
AFT |
Saccharomyces cerevisiae |
Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability |
Zhu et al., GR 2009 |
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| Alx3 |
O70137 |
Homeo |
Mus musculus |
aristaless 3 |
Berger et al., Cell 2008 |
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| Alx4 |
O35137 |
Homeo |
Mus musculus |
aristaless 4 |
Berger et al., Cell 2008 |
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| Arid3a |
Q62431 |
BRIGHT |
Mus musculus |
AT rich interactive domain 3A (Bright like) |
Badis et al., Science 2009 |
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| Arid5a |
Q8BI45 |
BRIGHT |
Mus musculus |
AT rich interactive domain 5A (Mrf1 like) |
Badis et al., Science 2009 |
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| Aro80 |
Q04052 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids |
Zhu et al., GR 2009 |
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| Arx |
O35085 |
Homeo |
Mus musculus |
aristaless related homeobox gene (Drosophila) |
Berger et al., Cell 2008 |
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| Ascl2 |
O35885 |
HLH |
Mus musculus |
achaete-scute complex homolog-like 2 (Drosophila) |
Badis et al., Science 2009 |
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| Asg1 |
P40467 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Proposed transcriptional activator, member of the Gal4p family of zinc cluster proteins |
Zhu et al., GR 2009 |
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| Atf1 |
P81269 |
BRLZ, BZIP_1, BZIP_2 |
Mus musculus |
activating transcription factor 1: Mus musculus activating transcription factor 1 (Atf1), mRNA |
Badis et al., Science 2009 |
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| Bapx1 |
P97503 |
Homeo |
Mus musculus |
bagpipe homeobox gene 1 homolog (Drosophila) |
Berger et al., Cell 2008 |
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| Barhl1 |
P63157 |
Homeo |
Mus musculus |
BarH-like 1 (Drosophila) |
Berger et al., Cell 2008 |
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| Barhl2 |
Q8VIB5 |
Homeo |
Mus musculus |
BarH-like 2 (Drosophila) |
Berger et al., Cell 2008 |
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| Barx1 |
Q9ER42 |
Homeo |
Mus musculus |
BarH-like homeobox 1 |
Berger et al., Cell 2008 |
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| Barx2 |
O08686 |
Homeo |
Mus musculus |
BarH-like homeobox 2 |
Berger et al., Cell 2008 |
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| Bas1 |
P22035 |
Myb |
Saccharomyces cerevisiae |
Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways; also involved in regulation of meiotic recombination at specific genes |
Zhu et al., GR 2009 |
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| Bbx |
Q8VBW5 |
HMG |
Mus musculus |
bobby sox homolog (Drosophila) |
Badis et al., Science 2009 |
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| Bcl6b |
O88282 |
ZnF_C2H2 |
Mus musculus |
B-cell CLL/lymphoma 6, member B: Mus musculus B-cell CLL/lymphoma 6, member B, mRNA |
Badis et al., Science 2009 |
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| Bhlhb2 |
O35185 |
HLH |
Mus musculus |
basic helix-loop-helix domain containing, class B2: Mus musculus basic helix-loop-helix domain containing, class B2 |
Badis et al., Science 2009 |
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| Bsx |
Q810B3 |
Homeo |
Mus musculus |
brain specific homeobox |
Berger et al., Cell 2008 |
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| Cart1 |
Q8C8B0 |
Homeo |
Mus musculus |
cartilage homeo protein 1 |
Berger et al., Cell 2008 |
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| Cbf1 |
P17106 |
HLH |
Saccharomyces cerevisiae |
Helix-loop-helix protein that binds the motif CACRTG, which is present at several sites including MET gene promoters and centromere DNA element I (CDEI); required for nucleosome positioning at this motif; targets Isw1p to DNA |
Berger et al., Nat Biotech 2006 |
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| Cbf1 |
P17106 |
HLH |
Saccharomyces cerevisiae |
Helix-loop-helix protein that binds the motif CACRTG, which is present at several sites including MET gene promoters and centromere DNA element I (CDEI); required for nucleosome positioning at this motif; targets Isw1p to DNA |
Zhu et al., GR 2009 |
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| Cdx1 |
P18111 |
Homeo |
Mus musculus |
caudal type homeo box 1 |
Berger et al., Cell 2008 |
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| Cdx2 |
P43241 |
Homeo |
Mus musculus |
caudal type homeo box 2 |
Berger et al., Cell 2008 |
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| Ceh-22 |
P41936 |
Homeo |
Caenorhabditis elegans |
Homeobox protein ceh-22: C.Elegans Homeobox |
Berger et al., Nat Biotech 2006 |
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| Cep3 |
P40969 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Essential kinetochore protein, component of the CBF3 complex that binds the CDEIII region of the centromere; contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain, and ... |
Zhu et al., GR 2009 |
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| Cgd2_3490 |
Q5CTD3 |
AP2 |
Cryptosporidium parvum |
putative transcription factor Cryptosporidium parvum, single AP2 domain, orthologous to PF14_0633 in Plasmodium falciparum |
De Silva et al., PNAS 2008 |
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| Cha4 |
P43634 |
Zn2Cys6 |
Saccharomyces cerevisiae |
DNA binding transcriptional activator, mediates serine/threonine activation of the catabolic L-serine (L-threonine) deaminase (CHA1); Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear clu... |
Zhu et al., GR 2009 |
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| CND-1 |
P46581 |
bHLH |
Caenorhabditis elegans |
C. elegans Neuro D homolog: cnd-1 encodes a basic helix-loop-helix protein that is most closely related to the vertebrate NeuroD transcription factors; during development, CND-1 is predicted to function as a transcriptional regulator whose activity is required for several aspects of motor neuron fate specification, including cell division patterns, proper spatiotemporal expression of fate-specific markers, and normal axonal morphology and pathfinding; CND-1::GFP expression begins in early embryogenesis (<20 cells) in four AB descendants and then continues in mitotically active AB-derived neuronal precursors, unidentified nuclei during gastrulation and enclosure, and postmitotic neurons in the head and ventral cord; at hatching CND-1::GFP expression is visible in ventral cord neurons, but this expression disappears completely by the end of the first larval stage; CND-1::GFP does not appear to be expressed in any non-neuronal ectodermal cells, as its expression does not overlap with that of LIN-26. |
Grove et al., Cell 2009 |
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| Cphx |
Q8BX39 |
Homeo |
Mus musculus |
cytoplasmic polyadenylated homeobox |
Berger et al., Cell 2008 |
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| Crx |
O54751 |
Homeo |
Mus musculus |
cone-rod homeobox containing gene |
Berger et al., Cell 2008 |
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| Cup9 |
P41817 |
Homeo |
Saccharomyces cerevisiae |
Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p an... |
Zhu et al., GR 2009 |
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| Cutl1 |
P70403 |
Homeo |
Mus musculus |
cut-like 1 (Drosophila) |
Berger et al., Cell 2008 |
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| Dbx1 |
P52950 |
Homeo |
Mus musculus |
developing brain homeobox 1 |
Berger et al., Cell 2008 |
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| Dbx2 |
Q8BZD0 |
Homeo |
Mus musculus |
developing brain homeobox 2 |
Berger et al., Cell 2008 |
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| Dlx1 |
Q64317 |
Homeo |
Mus musculus |
distal-less homeobox 1 |
Berger et al., Cell 2008 |
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| Dlx2 |
P40764 |
Homeo |
Mus musculus |
distal-less homeobox 2 |
Berger et al., Cell 2008 |
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| Dlx3 |
Q64205 |
Homeo |
Mus musculus |
distal-less homeobox 3 |
Berger et al., Cell 2008 |
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| Dlx4 |
P70436 |
Homeo |
Mus musculus |
distal-less homeobox 4 |
Berger et al., Cell 2008 |
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| Dlx5 |
P70396 |
Homeo |
Mus musculus |
distal-less homeobox 5 |
Berger et al., Cell 2008 |
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| Dmbx1 |
Q91ZK4 |
Homeo |
Mus musculus |
diencephalon/mesencephalon homeobox 1 |
Berger et al., Cell 2008 |
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| Dobox4 |
|
Homeo |
Mus musculus |
EST CN720839: E0811A05-5 NIA Mouse four-cell-Embryo cDNA library (Long) Mus musculus cDNA clone NIA:E0811A05 IMAGE:30906628 5-, mRNA sequence |
Berger et al., Cell 2008 |
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| Dobox5 |
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Homeo |
Mus musculus |
Formerly named ENSMUST00000057964.5 |
Berger et al., Cell 2008 |
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| Duxl |
Q3UY88 |
Homeo |
Mus musculus |
RIKEN cDNA 1110051B16 gene |
Berger et al., Cell 2008 |
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| E2F2 |
P56931 |
E2F_TDP |
Mus musculus |
E2F transcription factor 2 |
Badis et al., Science 2009 |
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| E2F3 |
O35261 |
E2F_TDP |
Mus musculus |
E2F transcription factor 3 |
Badis et al., Science 2009 |
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| Ecm22 |
Q05958 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Sterol regulatory element binding protein, regulates transcription of the sterol biosynthetic genes ERG2 and ERG3; member of the fungus-specific Zn[2]-Cys[6] binuclear cluster family of transcription |
Zhu et al., GR 2009 |
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| Egr1 |
P08046 |
ZnF_C2H2 |
Mus musculus |
early growth response 1 |
Badis et al., Science 2009 |
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| Ehf |
Q922E8 |
ETS |
Mus musculus |
ets homologous factor: Mus musculus EHF (Ehf) mRNA, complete cds |
Badis et al., Science 2009 |
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| Elf3 |
Q3UPW2 |
AT_hook, ETS |
Mus musculus |
E74-like factor 3 |
Badis et al., Science 2009 |
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| Emx2 |
Q04744 |
Homeo |
Mus musculus |
empty spiracles homolog 2 (Drosophila) |
Berger et al., Cell 2008 |
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| En1 |
P09065 |
Homeo |
Mus musculus |
engrailed 1 |
Berger et al., Cell 2008 |
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| En2 |
P09066 |
Homeo |
Mus musculus |
engrailed 2 |
Berger et al., Cell 2008 |
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| Eomes |
O54839 |
TBOX |
Mus musculus |
Eomesodermin homolog (Xenopus laevis): Mus musculus similar to Eomesodermin homolog (LOC235673), mRNA |
Badis et al., Science 2009 |
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| Esrra |
O08580 |
ZnF_C4 |
Mus musculus |
estrogen related receptor, alpha: Mus musculus estrogen related receptor, alpha (Esrra), mRNA. |
Badis et al., Science 2009 |
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| Esx1 |
Q9Z2U3 |
Homeo |
Mus musculus |
extraembryonic, spermatogenesis, homeobox 1 |
Berger et al., Cell 2008 |
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| Evx1 |
P23683 |
Homeo |
Mus musculus |
even skipped homeotic gene 1 homolog |
Berger et al., Cell 2008 |
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| Evx2 |
P49749 |
Homeo |
Mus musculus |
even skipped homeotic gene 2 homolog |
Berger et al., Cell 2008 |
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| Fhl1 |
P39521 |
Fork-head |
Saccharomyces cerevisiae |
Putative transcriptional regulator with similarity to DNA-binding domain of Drosophila forkhead; required for rRNA processing |
Zhu et al., GR 2009 |
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| Fkh1 |
P40466 |
Fork-head |
Saccharomyces cerevisiae |
Transcription factor of the forkhead family that regulates the cell cycle and pseudohyphal growth; also involved in chromatin silencing at HML and HMR |
Zhu et al., GR 2009 |
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| Fkh2 |
P41813 |
Fork_head |
Saccharomyces cerevisiae |
Transcription factor of the forkhead family that regulates the cell cycle and pseudohyphal growth; also involved in chromatin silencing at HML and HMR; potential Cdc28p substrate |
Zhu et al., GR 2009 |
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| Foxa2 |
P35583 |
FH |
Mus musculus |
forkhead box A2: Mus musculus forkhead box A2 (Foxa2) |
Badis et al., Science 2009 |
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| Foxj1 |
Q61660 |
FH |
Mus musculus |
forkhead box J1: forkhead box J1 [Mus musculus] |
Badis et al., Science 2009 |
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| Foxj3 |
Q8BUR3 |
FH |
Mus musculus |
forkhead box J3: Mus musculus similar to Putative forkhead box protein KIAA1041 (LOC230700), mRNA |
Badis et al., Science 2009 |
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| Foxk1 |
P42128 |
FH |
Mus musculus |
forkhead box K1: Mus musculus forkhead box K1 (Foxk1), transcript variant 1, mRNA. |
Badis et al., Science 2009 |
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| Foxl1 |
Q64731 |
FH |
Mus musculus |
forkhead box L1: M.musculus fkh-6 gene |
Badis et al., Science 2009 |
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| Gabpa |
Q00422 |
ETS |
Mus musculus |
GA repeat binding protein, alpha: Mus musculus GA repeat binding protein, alpha |
Badis et al., Science 2009 |
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| Gal4 |
P04386 |
Zn2Cys6 |
Saccharomyces cerevisiae |
DNA-binding transcription factor required for the activation of the GAL genes in response to galactose; repressed by Gal80p and activated by Gal3p |
Zhu et al., GR 2009 |
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| Gat1 |
P43574 |
Zf_GATA |
Saccharomyces cerevisiae |
Transcriptional activator of genes involved in nitrogen catabolite repression, member of the GATA family of DNA binding proteins; activity and localization regulated by nitrogen limitation and Ure2p |
Zhu et al., GR 2009 |
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| Gat3 |
Q07928 |
Zf_GATA |
Saccharomyces cerevisiae |
Protein containing GATA family zinc finger motifs |
Zhu et al., GR 2009 |
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| Gat4 |
P40569 |
Zf_GATA |
Saccharomyces cerevisiae |
Protein containing GATA family zinc finger motifs |
Zhu et al., GR 2009 |
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| Gata3 |
P23772 |
ZnF_GATA |
Mus musculus |
GATA binding protein 3: Mus musculus GATA binding protein 3 (Gata3), mRNA. |
Badis et al., Science 2009 |
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| Gata5 |
P97489 |
ZnF_GATA |
Mus musculus |
GATA binding protein 5 |
Badis et al., Science 2009 |
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| Gata6 |
Q61169 |
ZnF_GATA |
Mus musculus |
GATA binding protein 6 |
Badis et al., Science 2009 |
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| Gbx1 |
P82976 |
Homeo |
Mus musculus |
gastrulation brain homeobox 1 |
Berger et al., Cell 2008 |
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| Gbx2 |
P48031 |
Homeo |
Mus musculus |
gastrulation brain homeobox 2 |
Berger et al., Cell 2008 |
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| Gcm1 |
P70348 |
GCM |
Mus musculus |
glial cells missing homolog 1 (Drosophila) |
Badis et al., Science 2009 |
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| Gcn4 |
P03069 |
bZIP |
Saccharomyces cerevisiae |
Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels |
Zhu et al., GR 2009 |
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| Glis2 |
Q8R4X9 |
ZnF_C2H2 |
Mus musculus |
GLIS family zinc finger 2: GLIS family zinc finger 2 (Glis2), mRNA |
Badis et al., Science 2009 |
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| Gln3 |
P18494 |
Zf_GATA |
Saccharomyces cerevisiae |
Transcriptional activator of genes regulated by nitrogen catabolite repression (NCR), localization and activity regulated by quality of nitrogen source |
Zhu et al., GR 2009 |
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| Gm397 |
Q3URS2 |
ZnF_C2H2 |
Mus musculus |
gene model 397, (NCBI): Mus musculus similar to Zinc finger protein 58 (Zfp-58) (Zinc finger protein Mfg-1) (LOC212386), mRNA |
Badis et al., Science 2009 |
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| Gmeb1 |
Q9JL60 |
SAND |
Mus musculus |
glucocorticoid modulatory element binding protein 1: transcription termination factor 1, mRNA (cDNA clone MGC:69635 IMAGE:6847867), complete cds |
Badis et al., Science 2009 |
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| Gsc |
Q02591 |
Homeo |
Mus musculus |
goosecoid |
Berger et al., Cell 2008 |
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| Gsh2 |
P31316 |
Homeo |
Mus musculus |
genomic screened homeo box 2 |
Berger et al., Cell 2008 |
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| Gsm1 |
|
Zn2Cys6 |
Saccharomyces cerevisiae |
Putative zinc cluster protein of unknown function; computationally predicted involvement in oxidative phosphorylation, based on patterns of expression and sequence analysis |
Zhu et al., GR 2009 |
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| Gzf3 |
P42944 |
Zf_GATA |
Saccharomyces cerevisiae |
GATA zinc finger protein and Dal80p homolog that negatively regulates nitrogen catabolic gene expression by competing with Gat1p for GATA site binding; function requires a repressive carbon source;... |
Zhu et al., GR 2009 |
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| Hal9 |
Q12180 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decrease... |
Zhu et al., GR 2009 |
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| Hbp1 |
Q8R316 |
HMG |
Mus musculus |
high mobility group box transcription factor 1 |
Badis et al., Science 2009 |
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| Hdx |
Q14B70 |
Homeo |
Mus musculus |
Highly divergent homeobox |
Berger et al., Cell 2008 |
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| Hic1 |
Q9R1Y5 |
ZnF_C2H2 |
Mus musculus |
hypermethylated in cancer 1: Mus musculus hypermethylated in cancer 1 (Hic1) |
Badis et al., Science 2009 |
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| HLH-1 |
P22980 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 1: hlh-1 encodes a basic helix-loop-helix (bHLH) transcription factor that is the C. elegans ortholog of the myogenic regulatory factor (MRF) subgroup of bHLH proteins; in C. elegans, HLH-1 activity is required during embryogenesis for proper bodywall muscle development and function, but not for bodywall muscle cell fate specification, per se: hlh-1 null mutants generate the normal number of bodywall muscle cells, but the arrangement of these cells is disrupted and mutant animals exhibit weak and disorganized muscle contractions; however, ectopic expression of HLH-1 in the embryo is sufficient to convert nearly all embryonic cell types to a bodywall muscle-like fate; in regulating bodywall myogenesis, genetic studies indicate that HLH-1 acts together with the UNC-120/SRF and HND-1/HAND transcription factors, both of which can also induce muscle-like fates when overexpressed in embryos; in addition, in some cell lineages, hlh-1 likely lies downstream of the PAL-1 homeodomain protein required for specification of the C and D founder cell fates; HLH-1 is expressed in nuclei and first appears in bodywall muscle precursors beginning at the ~80-cell stage of embryogenesis; expression then continues in these cells and their differentiated descendants throughout embryonic, larval, and adult stages of development. |
Grove et al., Cell 2009 |
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| HLH-10 |
Q23579 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 10: none available |
Grove et al., Cell 2009 |
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| HLH-11 |
P34474 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 11: none available |
Grove et al., Cell 2009 |
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| HLH-14 |
Q09961 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 14: hlh-14 encodes a basic helix-loop-helix (bHLH) transcription factor that is one of five C. elegans Achaete-Scute family homologs; HLH-14 activity is required generally for normal egg-laying, movement, body morphology, and larval development; more specifically, HLH-14 is required for proper neuronal development, particularly for regulation of the asymmetric cell division that gives rise to the PVQ/HSN/PHB neuroblasts and for normal differentiation of these neuroblast descendants, including their cell division patterns, migrations, and neurotransmitter expression; in specifying neuronal cell fates, genetic evidence suggests that hlh-14 acts together with hlh-2, which encodes the C. elegans E/Daughterless ortholog; HLH-14 is expresed exclusively in the embryo and detected in the left and right PVQ/HSN/PHB neuroblasts and their descendants, as well as in other cells identified, tentatively, as anterior neuroblasts and posterior neuroblasts such as Caapa. |
Grove et al., Cell 2009 |
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| HLH-15 |
Q18590 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 15 : none available |
Grove et al., Cell 2009 |
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| HLH-19 |
Q20941 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 19 : none available |
Grove et al., Cell 2009 |
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| HLH-2 |
Q17588 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 2: hlh-2 encodes a Class I basic helix-loop-helix (bHLH) transcription factor that is the C. elegans ortholog of the mammalian E and Drosophila Daughterless transcriptional activators; HLH-2 activity is required for cell fate specifications occuring during embryonic and larval development that affect such processes as gonadogenesis, male tail formation, and programmed cell death; HLH-2 has been shown to dimerize with at least two C. elegans Acheate-scute homologs, LIN-32, a neural-specific protein with which it functions in male tail development and HLH-3, with which it is coexpressed in the nuclei of embryonic neuronal prescursors and with which it regulates the transcription of the EGL-1 cell death activator in the NSM sister cells; in gonadogenesis, HLH-2 is required for bestowing proAC competence on the cells that undergo the AC/VU (anchor cell/ventral uterine precursor) cell fate decision, for specification, differentiation, and function of the distal tip cell (DTC) and AC, including transcriptional regulation of the LAG-2 Delta-like ligand in the latter, and for formation of the uterine seam cell (utse); genetic analysis also suggests that HLH-2 functions with HLH-14, an additional Acaete-scute homolog, to specify the PVQ/HSN/PHB neuroblast cell lineage; HLH-2 is expressed in all nuclei of early embryos until the ~200-cell stage, when expression becomes increasingly restricted to neuronal cells and their immediate precursors; later expression is detected in, but not limited to, pharyngeal cells, anterior neurons, vulval and uterine muscles, the DTCs, the presumptive and mature AC, the Q neuroblast, and enteric muscles; comparative analysis of transcriptional and translational reporters indicates that hlh-2 is expressed in both the anchor cell and the ventral uterine (VU) precursor, but that expression in the latter is subject to post-transcriptional down-regulation; HLH-2 accumulation in the presumptive AC is the first detectable difference between the AC and VU precursors during the lateral specification event that distinguishes these two cell fates. |
Grove et al., Cell 2009 |
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| HLH-25 |
Q18054 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 25: hlh-25 encodes a REF-1-like protein with two bHLH domains that partially represses lag-2 transcription in ABa descendants (in response to a Notch signal, redundantly with HLH-27); lag-2 repression by HLH-25 may require UNC-37; HLH-25's paralogs include HLH-26 through HLH-29 and (more distantly) REF-1; hlh-25 is transcribed in the early MS lineage, has clustered binding sites for MED-1/2 in its promoter region, can be activated by ectopic MED-1, and loses activity in MED-1/2-deficient genetic backgrounds; HLH-25 is expressed in ABp granddaughters ~25 minutes after ABp first contacts an APX-1-expressing cell, and in ABa descendants after a second Notch interaction; HLH-25 is also expressed in four EMS granddaughters (MSaa, MSap, MSpa, MSpp) beginning at the 24-cell stage; ectopic HLH-25 can induce body muscle development in skn-1(RNAi);pal-1(RNAi) embryos that would otherwise lack muscle; HLH-25 is required for embryonic viability in mass RNAi assays. |
Grove et al., Cell 2009 |
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| HLH-26 |
Q18053 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 26: hlh-26 encodes a REF-1-like protein with two bHLH domains that represses lag-2 transcription in ABa descendants (in response to a Notch signal, redundantly with REF-1, HLH-27, HLH-29, and perhaps HLH-28) and tbx-37 transcription in EMS descendants (independently of Notch, redundantly with REF-1, HLH-27, HLH-29, and perhaps HLH-28); lag-2 repression by HLH-26 may require UNC-37; HLH-26's paralogs include HLH-25 through HLH-29 and (more distantly) REF-1; HLH-26 is not visibly expressed in EMS descendants, and has no obvious function in mass RNAi assays. |
Grove et al., Cell 2009 |
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| HLH-27 |
Q18056 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 27: hlh-27 encodes a REF-1-like protein with two bHLH domains, that represses lag-2 transcription in ABa descendants (in response to a Notch signal, redundantly with REF-1, HLH-25, HLH-26, HLH-29, and perhaps HLH-28) and tbx-37 transcription in EMS descendants (independently of Notch, redundantly with REF-1, HLH-26, HLH-29, and perhaps HLH-28); lag-2 repression by HLH-27 may require UNC-37; HLH-27's paralogs include HLH-25 through HLH-29 and (more distantly) REF-1; hlh-27 is transcribed in the early MS lineage, probably due to MED-1/2 binding of clustered sites in the hlh-27 promoter region; HLH-27 is expressed in ABp granddaughters ~25 minutes after ABp first contacts an APX-1-expressing cell, and in ABa descendants after a second Notch interaction; HLH-27 is also expressed in four EMS granddaughters (MSaa, MSap, MSpa, MSpp) beginning at the 24-cell stage, in a SKN-1-dependent manner; HLH-27 is required for embryonic viability in mass RNAi assays. |
Grove et al., Cell 2009 |
|
|
| HLH-29 |
Q19917 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 29: hlh-29 encodes a REF-1-like protein with two bHLH domains that represses lag-2 transcription in ABa descendants (in response to a Notch signal, redundantly with REF-1, HLH-26, and HLH-27) and tbx-37 transcription in EMS descendants (independently of Notch, redundantly with REF-1, HLH-26, HLH-27, and perhaps HLH-28); HLH-29 is identical to residues 24-262 of HLH-28, shares near-identical promoter regions in a inverted duplex, and is likely to be highly redundant with HLH-28; HLH-29 (with HLH-28) is also required for late embryonic viability, and for normal fat metabolism, yolk protein transport, gonadal and vulval development, bordering behavior, and chemosensory responses, and repression of tax-4 and osm-9 transcription; lag-2 repression by HLH-29 may require UNC-37; HLH-29's paralogs include HLH-25 through HLH-28 and (more distantly) REF-1; hlh-29 is transcribed in the early MS and E lineages, probably due to MED-1/2 binding of clustered sites in the hlh-28/hlh-29 shared promoter region; HLH-29 is expressed in ABp granddaughters ~25 minutes after ABp first contacts an APX-1-expressing cell, and in ABa descendants after a second Notch interaction; HLH-29 is also expressed in all EMS granddaughters beginning at the 24-cell stage, in a SKN-1-dependent manner; furthermore, HLH-29 is expressed in amphid and phasmid neurons, ALA and PVT neurons, chemosensory and mechanosensory neurons, ASI, ASK, PHA, PQR, and neurons of the anterior pharynx, as well as in vulva, somatic gonad, rectal glands, intestine, and larval pharyngeal muscle PM1, ventral posterior coelomocytes, spermatheca, and vulval muscles; hlh-28/29 mRNA is present throughout development, but varies roughly 30-fold in quantity, with 3.5-fold more mRNA in L1 larvae than in adults; ectopic HLH-29 can rescue the intestinal defect of ref-1(RNAi) embryos; hlh-28/29 transcription is inhibited by LIN-12 and MED-1. |
Grove et al., Cell 2009 |
|
|
| HLH-3 |
P90977 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 3: hlh-3 encodes a basic helix-loop-helix transcription factor homologous to Drosophila Achaete-scute; in vitro, HLH-3 can heterodimerize, and bind an E-box-containing probe, with HLH-2, the C. elegans E/daughterless ortholog with which it is coexpressed in the nuclei of embryonic neuronal precursors. |
Grove et al., Cell 2009 |
|
|
| HLH-30 |
P91527 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 30: W02C12.3 is orthologous to the human gene TRANSCRIPTION FACTOR BINDING TO IGHM ENHANCER 3 (TFE3; OMIM:314310), which when mutated leads to disease. |
Grove et al., Cell 2009 |
|
|
| HLH-4 |
P34555 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 4: none available |
Grove et al., Cell 2009 |
|
|
| HLH-8 |
Q11094 |
bHLH |
Caenorhabditis elegans |
Helix Loop Helix Protein 8: The hlh-8 gene encodes a helix-loop-helix protein required for normal muscle development, and hence for normal defecation and egg-laying. |
Grove et al., Cell 2009 |
|
|
| Hlx1 |
Q61670 |
Homeo |
Mus musculus |
H2.0-like homeo box 1 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Hlxb9 |
Q9QZW9 |
Homeo |
Mus musculus |
homeobox gene HB9 |
Berger et al., Cell 2008 |
|
|
| Hmbox1 |
Q8BJA3 |
Homeo |
Mus musculus |
homeobox containing 1 |
Berger et al., Cell 2008 |
|
|
| Hmx1 |
O70218 |
Homeo |
Mus musculus |
H6 homeo box 1 |
Berger et al., Cell 2008 |
|
|
| Hmx2 |
P43687 |
Homeo |
Mus musculus |
H6 homeo box 2 |
Berger et al., Cell 2008 |
|
|
| Hmx3 |
P42581 |
Homeo |
Mus musculus |
H6 homeo box 3 |
Berger et al., Cell 2008 |
|
|
| Hnf4a |
P49698 |
ZnF_C4 |
Mus musculus |
hepatic nuclear factor 4, alpha: Mus musculus hepatic nuclear factor 4, alpha (Hnf4a), mRNA |
Badis et al., Science 2009 |
|
|
| Homez |
Q80W88 |
Homeo |
Mus musculus |
homeodomain leucine zipper-encoding gene |
Berger et al., Cell 2008 |
|
|
| Hoxa1 |
P09022 |
Homeo |
Mus musculus |
homeo box A1 |
Berger et al., Cell 2008 |
|
|
| Hoxa10 |
P31310 |
Homeo |
Mus musculus |
homeo box A10 |
Berger et al., Cell 2008 |
|
|
| Hoxa11 |
P31311 |
Homeo |
Mus musculus |
homeo box A11 |
Berger et al., Cell 2008 |
|
|
| Hoxa13 |
PQ62424 |
Homeo |
Mus musculus |
homeo box A13 |
Berger et al., Cell 2008 |
|
|
| Hoxa2 |
P31245 |
Homeo |
Mus musculus |
homeo box A2 |
Berger et al., Cell 2008 |
|
|
| Hoxa3 |
P02831 |
Homeo |
Mus musculus |
homeo box A3: Mus musculus homeo box A3 (Hoxa3) |
Badis et al., Science 2009 |
|
|
| Hoxa3 |
P02831 |
Homeo |
Mus musculus |
homeo box A3: Mus musculus homeo box A3 (Hoxa3) |
Berger et al., Cell 2008 |
|
|
| Hoxa4 |
P06798 |
Homeo |
Mus musculus |
homeo box A4 |
Berger et al., Cell 2008 |
|
|
| Hoxa5 |
P09021 |
Homeo |
Mus musculus |
homeo box A5 |
Berger et al., Cell 2008 |
|
|
| Hoxa6 |
P09092 |
Homeo |
Mus musculus |
homeo box A6 |
Berger et al., Cell 2008 |
|
|
| Hoxa7 |
P02830 |
Homeo |
Mus musculus |
homeo box A7 |
Berger et al., Cell 2008 |
|
|
| Hoxa9 |
P09631 |
Homeo |
Mus musculus |
homeo box A9 |
Berger et al., Cell 2008 |
|
|
| Hoxb13 |
P70321 |
Homeo |
Mus musculus |
homeo box B13 |
Berger et al., Cell 2008 |
|
|
| Hoxb3 |
P09026 |
Homeo |
Mus musculus |
homeo box B3 |
Berger et al., Cell 2008 |
|
|
| Hoxb4 |
P10284 |
Homeo |
Mus musculus |
homeo box B4 |
Berger et al., Cell 2008 |
|
|
| Hoxb5 |
P09079 |
Homeo |
Mus musculus |
homeo box B5 |
Berger et al., Cell 2008 |
|
|
| Hoxb6 |
P09023 |
Homeo |
Mus musculus |
homeo box B6 |
Berger et al., Cell 2008 |
|
|
| Hoxb7 |
P09024 |
Homeo |
Mus musculus |
homeo box B7 |
Berger et al., Cell 2008 |
|
|
| Hoxb8 |
P09632 |
Homeo |
Mus musculus |
homeo box B8 |
Berger et al., Cell 2008 |
|
|
| Hoxb9 |
P20615 |
Homeo |
Mus musculus |
homeo box B9 |
Berger et al., Cell 2008 |
|
|
| Hoxc10 |
P31257 |
Homeo |
Mus musculus |
homeo box C10 |
Berger et al., Cell 2008 |
|
|
| Hoxc11 |
P31312 |
Homeo |
Mus musculus |
homeo box C11 |
Berger et al., Cell 2008 |
|
|
| Hoxc12 |
P31313 |
Homeo |
Mus musculus |
homeo box C12 |
Berger et al., Cell 2008 |
|
|
| Hoxc13 |
P50207 |
Homeo |
Mus musculus |
homeo box C13 |
Berger et al., Cell 2008 |
|
|
| Hoxc4 |
Q08624 |
Homeo |
Mus musculus |
homeo box C4 |
Berger et al., Cell 2008 |
|
|
| Hoxc5 |
P32043 |
Homeo |
Mus musculus |
homeo box C5 |
Berger et al., Cell 2008 |
|
|
| Hoxc6 |
P10629 |
Homeo |
Mus musculus |
homeo box C6 |
Berger et al., Cell 2008 |
|
|
| Hoxc8 |
P09025 |
Homeo |
Mus musculus |
homeo box C8 |
Berger et al., Cell 2008 |
|
|
| Hoxc9 |
P09633 |
Homeo |
Mus musculus |
homeo box C9 |
Berger et al., Cell 2008 |
|
|
| Hoxd1 |
Q01822 |
Homeo |
Mus musculus |
homeo box D1 |
Berger et al., Cell 2008 |
|
|
| Hoxd10 |
P28359 |
Homeo |
Mus musculus |
homeo box D10 |
Berger et al., Cell 2008 |
|
|
| Hoxd11 |
P23813 |
Homeo |
Mus musculus |
homeo box D11 |
Berger et al., Cell 2008 |
|
|
| Hoxd12 |
P23812 |
Homeo |
Mus musculus |
homeo box D12 |
Berger et al., Cell 2008 |
|
|
| Hoxd13 |
P70217 |
Homeo |
Mus musculus |
homeo box D13 |
Berger et al., Cell 2008 |
|
|
| Hoxd3 |
P09027 |
Homeo |
Mus musculus |
homeo box D3: M.musculus Hoxd-3 mRNA |
Berger et al., Cell 2008 |
|
|
| Hoxd8 |
P23463 |
Homeo |
Mus musculus |
homeo box D8 |
Berger et al., Cell 2008 |
|
|
| Ipf1 |
P52946 |
Homeo |
Mus musculus |
insulin promoter factor 1, homeodomain transcription factor |
Berger et al., Cell 2008 |
|
|
| IRC900814 |
|
SAND |
Mus musculus |
Arhgef12 |
Badis et al., Science 2009 |
|
|
| Irf3 |
P70671 |
IRF |
Mus musculus |
interferon regulatory factor 3 |
Badis et al., Science 2009 |
|
|
| Irf4 |
Q64287 |
IRF |
Mus musculus |
interferon regulatory factor 4 |
Badis et al., Science 2009 |
|
|
| Irf5 |
P56477 |
IRF |
Mus musculus |
interferon regulatory factor 5 |
Badis et al., Science 2009 |
|
|
| Irf6 |
Q8C2Z7 |
IRF |
Mus musculus |
interferon regulatory factor 6 |
Badis et al., Science 2009 |
|
|
| Irx2 |
P81066 |
Homeo |
Mus musculus |
Iroquois related homeobox 2 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Irx3 |
P81067 |
Homeo |
Mus musculus |
Iroquois related homeobox 3 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Irx4 |
Q9QY61 |
Homeo |
Mus musculus |
Iroquois related homeobox 4 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Irx5 |
Q9JKQ4 |
Homeo |
Mus musculus |
Iroquois related homeobox 5 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Irx6 |
Q9ER75 |
Homeo |
Mus musculus |
Iroquois related homeobox 6 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Isgf3g |
Q61179 |
IRF |
Mus musculus |
interferon dependent positive acting transcription factor 3 gamma: Mus musculus interferon dependent positive acting transcription factor 3 gamma (Isgf3g), mRNA |
Badis et al., Science 2009 |
|
|
| Isl2 |
Q9CXV0 |
Homeo |
Mus musculus |
insulin related protein 2 (islet 2) |
Berger et al., Cell 2008 |
|
|
| Isx |
A1A546 |
Homeo |
Mus musculus |
intestine-specific homeobox |
Berger et al., Cell 2008 |
|
|
| Jundm2 |
P97875 |
BRLZ, BZIP_1, BZIP_2 |
Mus musculus |
Jun dimerization protein 2: Mus musculus Jun dimerization protein 2 (Jundp2-pending), mRNA |
Badis et al., Science 2009 |
|
|
| Klf7 |
Q99JB0 |
ZnF_C2H2 |
Mus musculus |
Kruppel-like factor 7 (ubiquitous): Mus musculus Kruppel-like factor 7 (ubiquitous) (Klf7), mRNA |
Badis et al., Science 2009 |
|
|
| Lbx2 |
Q32M12 |
Homeo |
Mus musculus |
ladybird homeobox homolog 2 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Lef1 |
P27782 |
HMG |
Mus musculus |
lymphoid enhancer binding factor 1 |
Badis et al., Science 2009 |
|
|
| Leu3 |
P08638 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; positively regulated by alpha-isopropylmalate, an intermediate in ... |
Zhu et al., GR 2009 |
|
|
| Lhx1 |
P63006 |
Homeo |
Mus musculus |
LIM homeobox protein 1 |
Berger et al., Cell 2008 |
|
|
| Lhx2 |
Q9Z0S2 |
Homeo |
Mus musculus |
LIM homeobox protein 2 |
Berger et al., Cell 2008 |
|
|
| Lhx3 |
P50481 |
Homeo |
Mus musculus |
LIM homeobox protein 3 |
Berger et al., Cell 2008 |
|
|
| Lhx4 |
P53776 |
Homeo |
Mus musculus |
LIM homeobox protein 4 |
Berger et al., Cell 2008 |
|
|
| Lhx5 |
P61375 |
Homeo |
Mus musculus |
LIM homeobox protein 5 |
Berger et al., Cell 2008 |
|
|
| Lhx6 |
Q9R1R0 |
Homeo |
Mus musculus |
LIM homeobox protein 6 |
Berger et al., Cell 2008 |
|
|
| Lhx8 |
O35652 |
Homeo |
Mus musculus |
LIM homeobox protein 8 |
Berger et al., Cell 2008 |
|
|
| Lhx9 |
Q9WUH2 |
Homeo |
Mus musculus |
LIM homeobox protein 9 |
Berger et al., Cell 2008 |
|
|
| LIN-32 |
Q10574 |
bHLH |
Caenorhabditis elegans |
abnormal cell LINeage: lin-32 encodes a basic helix-loop-helix transcription factor that is required for development of several types of neurons, including the touch receptor neurons and the male sensory ray neurons. |
Grove et al., Cell 2009 |
|
|
| Lmx1a |
Q9JKU8 |
Homeo |
Mus musculus |
LIM homeobox transcription factor 1 alpha |
Berger et al., Cell 2008 |
|
|
| Lmx1b |
O88609 |
Homeo |
Mus musculus |
LIM homeobox transcription factor 1 beta |
Berger et al., Cell 2008 |
|
|
| LuxR |
P21308 |
HTH |
Vibrio harveyi |
HTH-type transcriptional regulator luxR: Regulatory protein of bacterial bioluminescence. It probably binds the autoinducer molecule and potentiates the transcription of the bioluminescence operon. (UniProt, 08/18/08) |
Pompeani et al., Mol Microbiol 2008 |
|
|
| Lys14 |
P40971 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer |
Zhu et al., GR 2009 |
|
|
| Mafb |
P54841 |
BRLZ |
Mus musculus |
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian): Mus musculus v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb), mRNA |
Badis et al., Science 2009 |
|
|
| Mafk |
Q61827 |
BRLZ |
Mus musculus |
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) |
Badis et al., Science 2009 |
|
|
| Matalpha2 |
|
Homeo |
Saccharomyces cerevisiae |
Homeobox-domain protein that, with Mcm1p, represses a-specific genes in haploids; acts with A1p to repress transcription of haploid-specific genes in diploids; one of two genes encoded by the MATal... |
Zhu et al., GR 2009 |
|
|
| Max |
P28574 |
HLH |
Mus musculus |
Max protein |
Badis et al., Science 2009 |
|
|
| Mbp1 |
P39678 |
HTH APSES-type |
Saccharomyces cerevisiae |
Transcription factor involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis |
Zhu et al., GR 2009 |
|
|
| Mcm1 |
P11746 |
MADS |
Saccharomyces cerevisiae |
Transcription factor involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes |
Zhu et al., GR 2009 |
|
|
| MDL-1 |
Q21663 |
bHLH |
Caenorhabditis elegans |
MAD-Like: mdl-1 encodes a basic helix-loop-helix (bHLH) protein similar to the vertebrate MAD transcriptional regulators; in vitro, MDL-1 can heterodimerize, and bind an E-box DNA sequence, with MXL-1, a C. elegans MAX-like bHLH protein; when expressed in rat embryonic fibroblasts, MDL-1 is able to suppress c-MYC/RAS-induced cell transformation, in a manner dependent upon an intact, predicted SIN3 interaction domain; mdl-1::gfp promoter fusions are expressed in a number of different tissues, including the posterior intestine, anterior and ventral cord neurons, pharyngeal and body wall muscles, somatic gonad precursors, and hypodermal cells; yeast one-hybrid and ChIP experiments indicate that DAF-3/Smad can bind the mdl-1 promoter; in addition, mdl-1 pharyngeal expression is specifically increased in daf-3(RNAi) animals, suggesting that DAF-3 directly negatively regulates mdl-1 transcription in pharyngeal tissue during dauer formation. |
Grove et al., Cell 2009 |
|
|
| Meis1 |
Q60954 |
Homeo |
Mus musculus |
myeloid ecotropic viral integration site 1 |
Berger et al., Cell 2008 |
|
|
| Meox1 |
P32442 |
Homeo |
Mus musculus |
mesenchyme homeobox 1 |
Berger et al., Cell 2008 |
|
|
| Met32 |
Q12041 |
Zf_C2H2 |
Saccharomyces cerevisiae |
Zinc-finger DNA-binding protein, involved in regulating expression of the methionine biosynthetic genes, similar to Met31p |
Zhu et al., GR 2009 |
|
|
| Mga1 |
P53050 |
HSF_DNA-bind |
Saccharomyces cerevisiae |
Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants |
Zhu et al., GR 2009 |
|
|
| Mig1 |
P27705 |
Zf_C2H2 |
Saccharomyces cerevisiae |
Transcription factor involved in glucose repression; C2H2 zinc finger protein similar to mammalian Egr and Wilms tumor proteins |
Zhu et al., GR 2009 |
|
|
| Mig2 |
P53035 |
Zf_C2H2 |
Saccharomyces cerevisiae |
Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter |
Zhu et al., GR 2009 |
|
|
| Mig3 |
P39943 |
Zf_C2H2 |
Saccharomyces cerevisiae |
Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, a... |
Zhu et al., GR 2009 |
|
|
| Mrg1 |
P97367 |
Homeo |
Mus musculus |
myeloid ecotropic viral integration site-related gene 1 |
Berger et al., Cell 2008 |
|
|
| Mrg2 |
P97368 |
Homeo |
Mus musculus |
myeloid ecotropic viral integration site-related gene 2 |
Berger et al., Cell 2008 |
|
|
| Msx1 |
P13297 |
Homeo |
Mus musculus |
homeo box, msh-like 1 |
Berger et al., Cell 2008 |
|
|
| Msx2 |
Q03358 |
Homeo |
Mus musculus |
homeo box, msh-like 2 |
Berger et al., Cell 2008 |
|
|
| Msx3 |
P70354 |
Homeo |
Mus musculus |
homeo box, msh-like 3 |
Berger et al., Cell 2008 |
|
|
| Mtf1 |
Q07243 |
ZnF_C2H2 |
Mus musculus |
metal response element binding transcription factor 1: Metal response element binding transcription factor 1 |
Badis et al., Science 2009 |
|
|
| MXL-1 |
P90982 |
bHLH |
Caenorhabditis elegans |
MaX-Like: mxl-1 encodes a basic helix-loop-helix protein similar to the vertebrate MAX transcriptional regulators; in vitro, MXL-1 can heterodimerize, and bind an E-box DNA sequence, with MDL-1, a C. elegans MAD-like bHLH protein; mxl-1::gfp reporter fusions are expressed in the posterior intestine and in head and tail neurons. |
Grove et al., Cell 2009 |
|
|
| MXL-3 |
Q18711 |
bHLH |
Caenorhabditis elegans |
MaX-Like: none available |
Grove et al., Cell 2009 |
|
|
| Myb |
P06876 |
SANT |
Mus musculus |
myeloblastosis oncogene: Mus musculus myeloblastosis oncogene (Myb) |
Badis et al., Science 2009 |
|
|
| Mybl1 |
P51960 |
SANT |
Mus musculus |
myeloblastosis oncogene-like 1: myeloblastosis oncogene-like 1 (Mybl1), mRNA |
Badis et al., Science 2009 |
|
|
| Myf6 |
P15375 |
BASIC, HLH |
Mus musculus |
myogenic factor 6 |
Badis et al., Science 2009 |
|
|
| Ndt80 |
P38830 |
NDT80_PhoG |
Saccharomyces cerevisiae |
Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombination; activates middle sporulation genes; competes with Sum1p for binding to promoters containin... |
Zhu et al., GR 2009 |
|
|
| Nhp6a |
P11632 |
HMG_box |
Saccharomyces cerevisiae |
High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Bp; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to ce... |
Zhu et al., GR 2009 |
|
|
| Nhp6b |
P11633 |
HMG_box |
Saccharomyces cerevisiae |
High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Ap; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to ce... |
Zhu et al., GR 2009 |
|
|
| Nkx1-1 |
O08713 |
Homeo |
Mus musculus |
NK1 transcription factor related, locus 1 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Nkx1-2 |
P42580 |
Homeo |
Mus musculus |
NK1 transcription factor related, locus 2 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Nkx2-2 |
P42586 |
Homeo |
Mus musculus |
NK2 transcription factor related, locus 2 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Nkx2-3 |
P97334 |
Homeo |
Mus musculus |
NK2 transcription factor related, locus 3 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Nkx2-4 |
Q9EQM3 |
Homeo |
Mus musculus |
NK2 transcription factor related, locus 4 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Nkx2-5 |
P42582 |
Homeo |
Mus musculus |
NK2 transcription factor related, locus 5 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Nkx2-6 |
P43688 |
Homeo |
Mus musculus |
NK2 transcription factor related, locus 6 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Nkx2-9 |
O70584 |
Homeo |
Mus musculus |
NK2 transcription factor related, locus 9 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Nkx3-1 |
P97436 |
Homeo |
Mus musculus |
NK-3 transcription factor, locus 1 (Drosophila): Mus musculus homeobox-containing protein Nkx-3.1 mRNA |
Berger et al., Cell 2008 |
|
|
| Nkx3-1 |
P97436 |
Homeo |
Mus musculus |
NK-3 transcription factor, locus 1 (Drosophila): Mus musculus homeobox-containing protein Nkx-3.1 mRNA |
Badis et al., Science 2009 |
|
|
| Nkx6-1 |
Q99MA9 |
Homeo |
Mus musculus |
NK6 transcription factor related, locus 1 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Nkx6-3 |
Q9D2W8 |
Homeo |
Mus musculus |
NK6 transcription factor related, locus 3 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Nr2f2 |
P43135 |
ZnF_C4 |
Mus musculus |
nuclear receptor subfamily 2, group F, member 2: Mus musculus nuclear receptor subfamily 2, group F, member 2 (Nr2f2), transcript variant 1, mRNA. |
Badis et al., Science 2009 |
|
|
| Nrg1 |
Q03125 |
Zf_C2H2 |
Saccharomyces cerevisiae |
Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline p... |
Zhu et al., GR 2009 |
|
|
| Nsy-7 |
Q4PIU8 |
Distant similarity to homeodomain |
Caenorhabditis elegans |
Nsy-7: Putative uncharacterized protein |
Lesch et al., GD 2009 |
|
|
| Oaf1 |
P39720 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis |
Zhu et al., GR 2009 |
|
|
| Obox1 |
Q9D350 |
Homeo |
Mus musculus |
oocyte specific homeobox 1 |
Berger et al., Cell 2008 |
|
|
| Obox2 |
Q8VHG7 |
Homeo |
Mus musculus |
oocyte specific homeobox 2 |
Berger et al., Cell 2008 |
|
|
| Obox3 |
Q8VHG6 |
Homeo |
Mus musculus |
oocyte specific homeobox 3 |
Berger et al., Cell 2008 |
|
|
| Obox5 |
Q7TPZ5 |
Homeo |
Mus musculus |
oocyte specific homeobox 5 |
Berger et al., Cell 2008 |
|
|
| Obox6 |
Q8VHG3 |
Homeo |
Mus musculus |
oocyte specific homeobox 6 |
Berger et al., Cell 2008 |
|
|
| Oct-1 |
P14859 |
POU |
Homo sapiens |
"POU domain, class 2, transcription factor 1": "POU domain, class 2, transcription factor 1" |
Berger et al., Nat Biotech 2006 |
|
|
| Og2x |
P70367 |
Homeo |
Mus musculus |
OG2 homeobox gene |
Berger et al., Cell 2008 |
|
|
| Osr1 |
Q9WVG7 |
ZnF_C2H2 |
Mus musculus |
odd-skipped related 1 (Drosophila): Mus musculus HCM5520 gene, VIRTUAL TRANSCRIPT, partial sequence, genomic survey sequence |
Badis et al., Science 2009 |
|
|
| Osr2 |
Q91ZD1 |
ZnF_C2H2 |
Mus musculus |
odd-skipped related 2 (Drosophila): odd-skipped related 2 (Drosophila) (Osr2), mRNA |
Badis et al., Science 2009 |
|
|
| Otp |
O09113 |
Homeo |
Mus musculus |
orthopedia homolog (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Otx1 |
P80205 |
Homeo |
Mus musculus |
orthodenticle homolog 1 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Otx2 |
P80206 |
Homeo |
Mus musculus |
orthodenticle homolog 2 (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Pax4 |
P32115 |
Homeo, PAX |
Mus musculus |
paired box gene 4 |
Berger et al., Cell 2008 |
|
|
| Pax6 |
P63015 |
Homeo, PAX |
Mus musculus |
paired box gene 6 |
Berger et al., Cell 2008 |
|
|
| Pax7 |
P47239 |
Homeo, PAX |
Mus musculus |
paired box gene 7 |
Berger et al., Cell 2008 |
|
|
| Pbf1 |
P34219 |
Myb |
Saccharomyces cerevisiae |
Myb domain-containing protein YBL054W |
Zhu et al., GR 2009 |
|
|
| Pbf2 |
P40059 |
Myb |
Saccharomyces cerevisiae |
Protein of unknown function, involved in telomeric gene silencing and filamentation |
Zhu et al., GR 2009 |
|
|
| Pbx1 |
P41778 |
Homeo |
Mus musculus |
pre B-cell leukemia transcription factor 1 |
Berger et al., Cell 2008 |
|
|
| Pdr1 |
P12383 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance ... |
Zhu et al., GR 2009 |
|
|
| PF14_0633 |
Q8IKH2 |
AP2 |
Plasmodium falciparum |
putative Plasmodium falciparum transcription factor, single AP2 domain |
De Silva et al., PNAS 2008 |
|
|
| PFF0200c |
Q6LFM5 |
AP2 |
Plasmodium falciparum |
putative Plasmodium falciparum transcription factor, tandem double AP2 domain |
De Silva et al., PNAS 2008 |
|
|
| Phd1 |
P36093 |
HTH APSES-type |
Saccharomyces cerevisiae |
Transcriptional activator that enhances pseudohyphal growth; regulates expression of FLO11, an adhesin required for pseudohyphal filament formation; similar to StuA, an A. nidulans developmental re.. |
Zhu et al., GR 2009 |
|
|
| Pho2 |
P07269 |
Homeo |
Saccharomyces cerevisiae |
Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction |
Zhu et al., GR 2009 |
|
|
| Pho4 |
P07270 |
HLH |
Saccharomyces cerevisiae |
Basic helix-loop-helix (bHLH) transcription factor; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability |
Zhu et al., GR 2009 |
|
|
| Phox2a |
Q62066 |
Homeo |
Mus musculus |
paired-like homeobox 2a |
Berger et al., Cell 2008 |
|
|
| Phox2b |
O35690 |
Homeo |
Mus musculus |
paired-like homeobox 2b |
Berger et al., Cell 2008 |
|
|
| Pitx1 |
P70314 |
Homeo |
Mus musculus |
paired-like homeodomain transcription factor 1 |
Berger et al., Cell 2008 |
|
|
| Pitx2 |
P97474 |
Homeo |
Mus musculus |
paired-like homeodomain transcription factor 2 |
Berger et al., Cell 2008 |
|
|
| Pitx3 |
O35160 |
Homeo |
Mus musculus |
paired-like homeodomain transcription factor 3 |
Berger et al., Cell 2008 |
|
|
| Pknox1 |
O70477 |
Homeo |
Mus musculus |
Pbx/knotted 1 homeobox |
Berger et al., Cell 2008 |
|
|
| Pknox2 |
Q8BG99 |
Homeo |
Mus musculus |
Pbx/knotted 1 homeobox 2 |
Berger et al., Cell 2008 |
|
|
| Plagl1 |
O35745 |
ZnF_C2H2 |
Mus musculus |
Pleiomorphic adenoma gene-like 1: Mus musculus similar to zinc finger protein regulator of apoptosis and cell cycle arrest (Zac1), mRNA |
Badis et al., Science 2009 |
|
|
| Pou1f1 |
Q00286 |
Homeo, POU |
Mus musculus |
pituitary specific transcription factor 1 |
Berger et al., Cell 2008 |
|
|
| Pou2f1 |
P25425 |
Homeo, POU |
Mus musculus |
POU domain, class 2, transcription factor 1 |
Berger et al., Cell 2008 |
|
|
| Pou2f2 |
Q00196 |
Homeo, POU |
Mus musculus |
POU domain, class 2, transcription factor 2 |
Berger et al., Cell 2008 |
|
|
| Pou2f3 |
P31362 |
Homeo, POU |
Mus musculus |
POU domain, class 2, transcription factor 3 |
Berger et al., Cell 2008 |
|
|
| Pou3f1 |
P21952 |
Homeo, POU |
Mus musculus |
POU domain, class 3, transcription factor 1 |
Berger et al., Cell 2008 |
|
|
| Pou3f2 |
P31360 |
Homeo, POU |
Mus musculus |
POU domain, class 3, transcription factor 2 |
Berger et al., Cell 2008 |
|
|
| Pou3f3 |
P31361 |
Homeo, POU |
Mus musculus |
POU domain, class 3, transcription factor 3 |
Berger et al., Cell 2008 |
|
|
| Pou3f4 |
P62515 |
Homeo, POU |
Mus musculus |
POU domain, class 3, transcription factor 4 |
Berger et al., Cell 2008 |
|
|
| Pou4f3 |
P63955 |
Homeo, POU |
Mus musculus |
POU domain, class 4, transcription factor 3 |
Berger et al., Cell 2008 |
|
|
| Pou6f1 |
Q07916 |
Homeo, POU |
Mus musculus |
POU domain, class 6, transcription factor 1 |
Berger et al., Cell 2008 |
|
|
| Prop1 |
P97458 |
Homeo |
Mus musculus |
paired like homeodomain factor 1 |
Berger et al., Cell 2008 |
|
|
| Prrx1 |
P63013 |
Homeo |
Mus musculus |
paired related homeobox 1 |
Berger et al., Cell 2008 |
|
|
| Prrx2 |
Q06348 |
Homeo |
Mus musculus |
paired related homeobox 2 |
Berger et al., Cell 2008 |
|
|
| Put3 |
P25502 |
Zn2Cys6 |
Saccharomyces cerevisiae |
"Transcriptional activator of proline utilization genes, constitutively binds PUT1 and PUT2 promoter sequences and undergoes a conformational change to form the active state; has a Zn(2)-Cys(6) binu..." |
Zhu et al., GR 2009 |
|
|
| Rap1 |
P11938 |
Myb |
Saccharomyces cerevisiae |
"DNA-binding protein involved in either activation or repression of transcription, depending on binding site context; also binds telomere sequences and plays a role in telomeric position effect (sil..." |
Zhu et al., GR 2009 |
|
|
| Rap1 |
P11938 |
Myb |
Saccharomyces cerevisiae |
"DNA-binding protein involved in either activation or repression of transcription, depending on binding site context; also binds telomere sequences and plays a role in telomeric position effect (sil..." |
Berger et al., Nat Biotech 2006 |
|
|
| Rara |
P11416 |
ZnF_C4 |
Mus musculus |
retinoic acid receptor, alpha |
Badis et al., Science 2009 |
|
|
| Rax |
O35602 |
Homeo |
Mus musculus |
retina and anterior neural fold homeobox |
Berger et al., Cell 2008 |
|
|
| Rdr1 |
Q08904 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins |
Zhu et al., GR 2009 |
|
|
| Rds1 |
P25611 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Zinc cluster protein involved in conferring resistance to cycloheximide |
Zhu et al., GR 2009 |
|
|
| Rds2 |
P19541 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Zinc cluster protein involved in conferring resistance to ketoconazole |
Zhu et al., GR 2009 |
|
|
| REF-1 |
Q22069 |
bHLH |
Caenorhabditis elegans |
REgulator of Fusion: ref-1 encodes a protein with two basic helix-loop-helix (bHLH) domains that is distantly related to the hairy/Enhancer of split subfamily of bHLH transcription factors; REF-1 is required in hermaphrodites during early larval development for regulating the pattern of posterior Pn.p hypodermal cell fusions, primarily through regulation of MAB-5 homeodomain protein activity; REF-1 is also required for head morphogenesis and specification of the V6 lateral seam cell fate; in males, ref-1 is a target of MAB-3 transcriptional repression which in turn, promotes expression of LIN-32, a proneural bHLH transcription factor. |
Grove et al., Cell 2009 |
|
|
| Rfx3 |
P48381 |
RFX |
Mus musculus |
regulatory factor X, 3 (influences HLA class II expression) |
Badis et al., Science 2009 |
|
|
| Rfx4 |
Q8HWA6 |
RFX |
Mus musculus |
regulatory factor X, 4 (influences HLA class II expression) |
Badis et al., Science 2009 |
|
|
| Rfxdc2 |
Q8CB07 |
RFX |
Mus musculus |
regulatory factor X domain containing 2 homolog (human): AK138890 |
Badis et al., Science 2009 |
|
|
| Rgt1 |
P32862 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose; binds to promoters and acts both as a transcriptional activator ... |
Zhu et al., GR 2009 |
|
|
| Rhox11 |
Q810N8 |
Homeo |
Mus musculus |
reproductive homeobox 11 |
Berger et al., Cell 2008 |
|
|
| Rhox6 |
Q8BPD6 |
Homeo |
Mus musculus |
reproductive homeobox 6 |
Berger et al., Cell 2008 |
|
|
| Rph1 |
P39956 |
Zf_C2H2 |
Saccharomyces cerevisiae |
Transcriptional repressor of PHR1, which is a photolyase induced by DNA damage; binds to AG(4) (C(4)T) sequence upstream of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC... |
Zhu et al., GR 2009 |
|
|
| Rpn4 |
Q03465 |
Zf_C2H2 |
Saccharomyces cerevisiae |
Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally reg... |
Zhu et al., GR 2009 |
|
|
| Rsc3 |
Q06639 |
Zn2Cys6 |
Saccharomyces cerevisiae |
One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; essential gene required for regulation of ribosomal protein genes and the cell wall/stress response; highly similar to |
Zhu et al., GR 2009 |
|
|
| Rsc30 |
P38781 |
Zn2Cys6 |
Saccharomyces cerevisiae |
One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; non-essential gene required for regulation of ribosomal protein genes and the cell wall/stress response; highly similar... |
Zhu et al., GR 2009 |
|
|
| Rtg3 |
P38165 |
HLH |
Saccharomyces cerevisiae |
Basic helix-loop-helix-leucine zipper (bHLH/Zip) transcription factor that forms a complex with another bHLH/Zip protein, Rtg1p, to activate the retrograde (RTG) and TOR pathways |
Zhu et al., GR 2009 |
|
|
| Rxra |
P28700 |
ZnF_C4 |
Mus musculus |
retinoid X receptor alpha: retinoid X receptor alpha (Rxra), mRNA |
Badis et al., Science 2009 |
|
|
| Sfl1 |
P20134 |
HSF_DNA-bind |
Saccharomyces cerevisiae |
Transcription repressor involved in regulation of flocculation-related genes, inhibits transcription by recruiting general corepressor Cyc8p-Tup1p to different promoters; negatively regulated by cA... |
Zhu et al., GR 2009 |
|
|
| Sfp1 |
P32432 |
Zf_C2H2 |
Saccharomyces cerevisiae |
Transcription factor that controls expression of many ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, in... |
Zhu et al., GR 2009 |
|
|
| Sfpi1 |
P17433 |
ETS |
Mus musculus |
SFFV proviral integration 1: Mus musculus SFFV proviral integration 1 (Sfpi1), mRNA |
Badis et al., Science 2009 |
|
|
| Shox2 |
P70390 |
Homeo |
Mus musculus |
short stature homeobox 2 |
Berger et al., Cell 2008 |
|
|
| Sip4 |
P46954 |
Zn2Cys6 |
Saccharomyces cerevisiae |
C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1... |
Zhu et al., GR 2009 |
|
|
| Six1 |
Q62231 |
Homeo |
Mus musculus |
sine oculis-related homeobox 1 homolog (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Six2 |
Q62232 |
Homeo |
Mus musculus |
sine oculis-related homeobox 2 homolog (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Six3 |
Q62233 |
Homeo |
Mus musculus |
sine oculis-related homeobox 3 homolog (Drosophila): Mus musculus sine oculis-related homeobox 3 homolog (Drosophila) (Six3), mRNA. |
Berger et al., Cell 2008 |
|
|
| Six4 |
Q61321 |
Homeo |
Mus musculus |
sine oculis-related homeobox 4 homolog (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Six6 |
Q9QZ28 |
Homeo |
Mus musculus |
sine oculis-related homeobox 6 homolog (Drosophila) |
Berger et al., Cell 2008 |
|
|
| Six6 |
Q9QZ28 |
Homeo |
Mus musculus |
sine oculis-related homeobox 6 homolog (Drosophila) |
Badis et al., Science 2009 |
|
|
| Skn7 |
P38889 |
HSF_DNA-bind |
Saccharomyces cerevisiae |
Nuclear response regulator and transcription factor, part of a branched two-component signaling system; required for optimal induction of heat-shock genes in response to oxidative stress; |
Zhu et al., GR 2009 |
|
|
| Smad3 |
Q8BUN5 |
DWA |
Mus musculus |
MAD homolog 3 (Drosophila) |
Badis et al., Science 2009 |
|
|
| Smp1 |
P38128 |
MADS |
Saccharomyces cerevisiae |
Putative transcription factor involved in regulating the response to osmotic stress; member of the MADS-box family of transcription factors |
Zhu et al., GR 2009 |
|
|
| Sox1 |
P53783 |
HMG |
Mus musculus |
SRY-box containing gene 1 |
Badis et al., Science 2009 |
|
|
| Sox11 |
Q04889 |
HMG |
Mus musculus |
SRY-box containing gene 11 |
Badis et al., Science 2009 |
|
|
| Sox12 |
Q04890 |
HMG |
Mus musculus |
SRY-box containing gene 12 |
Badis et al., Science 2009 |
|
|
| Sox13 |
Q04891 |
HMG |
Mus musculus |
SRY-box containing gene 13: nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100, mRNA (cDNA clone MGC:35934 IMAGE:3672913), complete cds |
Badis et al., Science 2009 |
|
|
| Sox14 |
Q04892 |
HMG |
Mus musculus |
SRY-box containing gene 14: Mus musculus SRY-box containing gene 14, mRNA |
Badis et al., Science 2009 |
|
|
| Sox15 |
P43267 |
HMG |
Mus musculus |
SRY-box containing gene 15 |
Badis et al., Science 2009 |
|
|
| Sox17 |
Q61473 |
HMG |
Mus musculus |
SRY-box containing gene 17 |
Badis et al., Science 2009 |
|
|
| Sox18 |
P43680 |
HMG |
Mus musculus |
SRY-box containing gene 18 |
Badis et al., Science 2009 |
|
|
| Sox21 |
Q811W0 |
HMG |
Mus musculus |
SRY-box containing gene 21 |
Badis et al., Science 2009 |
|
|
| Sox30 |
Q8CGW4 |
HMG |
Mus musculus |
SRY-box containing gene 30: Mus musculus SRY-box containing gene 30 (Sox30) |
Badis et al., Science 2009 |
|
|
| Sox4 |
Q06945 |
HMG_box |
Homo sapiens |
SRY (sex determining region Y)-box 4 : This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function |
Scharer et al., CR 2009 |
|
|
| Sox4 |
Q06831 |
HMG |
Mus musculus |
SRY-box containing gene 4: Mus musculus BAC Clone 262c6 RPCI-23, complete sequence |
Badis et al., Science 2009 |
|
|
| Sox5 |
P35710 |
HMG |
Mus musculus |
SRY-box containing gene 5 |
Badis et al., Science 2009 |
|
|
| Sox7 |
P40646 |
HMG |
Mus musculus |
SRY-box containing gene 7 |
Badis et al., Science 2009 |
|
|
| Sox8 |
Q04886 |
HMG |
Mus musculus |
SRY-box containing gene 8: SRY-box containing gene 8, mRNA (cDNA clone MGC:78314 IMAGE:6306276), complete cds |
Badis et al., Science 2009 |
|
|
| Sp100 |
O35892 |
SAND |
Mus musculus |
nuclear antigen Sp100: PREDICTED: Mus musculus nuclear antigen Sp100 (Sp100) |
Badis et al., Science 2009 |
|
|
| Sp4 |
Q62445 |
ZnF_C2H2 |
Mus musculus |
trans-acting transcription factor 4: Mus musculus similar to trans-acting transcription factor 4 (LOC211769), mRNA |
Badis et al., Science 2009 |
|
|
| Spdef |
Q9WTP3 |
ETS |
Mus musculus |
SAM pointed domain containing ets transcription factor: Mus musculus prostate specific ets transcription factor (Pse-pending), mRNA |
Badis et al., Science 2009 |
|
|
| Spt15 |
P13393 |
TBP |
Saccharomyces cerevisiae |
TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability |
Zhu et al., GR 2009 |
|
|
| Srd1 |
P09007 |
Zf_GATA |
Saccharomyces cerevisiae |
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation |
Zhu et al., GR 2009 |
|
|
| Srf |
Q9JM73 |
MADS |
Mus musculus |
serum response factor |
Badis et al., Science 2009 |
|
|
| Sry |
Q05738 |
HMG |
Mus musculus |
sex determining region of Chr Y |
Badis et al., Science 2009 |
|
|
| Stb3 |
Q12427 |
|
Saccharomyces cerevisiae |
Protein that binds Sin3p in a two-hybrid assay |
Zhu et al., GR 2009 |
|
|
| Stp2 |
P38704 |
Zf_C2H2 |
Saccharomyces cerevisiae |
Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes |
Zhu et al., GR 2009 |
|
|
| Stp4 |
|
Zf_C2H2 |
Saccharomyces cerevisiae |
Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p |
Zhu et al., GR 2009 |
|
|
| Sum1 |
P46676 |
AT_hook |
Saccharomyces cerevisiae |
Transcriptional repressor required for mitotic repression of middle sporulation-specific genes; involved in telomere maintenance, regulated by the pachytene checkpoint |
Zhu et al., GR 2009 |
|
|
| Sut2 |
Q12286 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Putative transcription factor; multicopy suppressor of mutations that cause low activity of the cAMP/protein kinase A pathway; highly similar to Sut1p |
Zhu et al., GR 2009 |
|
|
| Tbf1 |
Q02457 |
Myb |
Saccharomyces cerevisiae |
Telobox-containing general regulatory factor; binds to TTAGGG repeats within subtelomeric anti-silencing regions (STARs) and possibly throughout the genome and mediates their insulating capacity by... |
Zhu et al., GR 2009 |
|
|
| Tbp |
P29037 |
TBP |
Mus musculus |
TATA box binding protein |
Badis et al., Science 2009 |
|
|
| Tbs1 |
P38114 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Probable Zn-finger protein |
Zhu et al., GR 2009 |
|
|
| Tcf1 |
Q66JY7 |
Homeo |
Mus musculus |
transcription factor 1: Mus musculus transcription factor 1 (Tcf1), mRNA. |
Berger et al., Cell 2008 |
|
|
| Tcf1 |
Q66JY7 |
Homeo |
Mus musculus |
transcription factor 1: Mus musculus transcription factor 1 (Tcf1), mRNA. |
Badis et al., Science 2009 |
|
|
| Tcf2 |
P27889 |
Homeo |
Mus musculus |
transcription factor 2: TCF2 gene, VIRTUAL TRANSCRIPT, partial sequence, genomic survey sequence |
Berger et al., Cell 2008 |
|
|
| Tcf3 |
Q9Z1J1 |
HMG |
Mus musculus |
transcription factor 3 |
Badis et al., Science 2009 |
|
|
| Tcf7 |
Q00417 |
HMG |
Mus musculus |
Transcription factor 7, T-cell specific |
Badis et al., Science 2009 |
|
|
| Tcf7l2 |
Q924A0 |
HMG |
Mus musculus |
transcription factor 7-like 2, T-cell specific, HMG-box |
Badis et al., Science 2009 |
|
|
| Tcfap2a |
P34056 |
AP-2 |
Mus musculus |
transcription factor AP-2, alpha: Mus musculus transcription factor AP-2, alpha, mRNA |
Badis et al., Science 2009 |
|
|
| Tcfap2b |
Q61313 |
AP-2 |
Mus musculus |
transcription factor AP-2 beta |
Badis et al., Science 2009 |
|
|
| Tcfap2c |
Q61312 |
AP-2 |
Mus musculus |
transcription factor AP-2, gamma: Mus musculus transcription factor AP-2, gamma, mRNA (cDNA clone MGC:5992 IMAGE:3592762), complete cds |
Badis et al., Science 2009 |
|
|
| Tcfap2e |
Q6VUP9 |
AP-2 |
Mus musculus |
transcription factor AP-2, epsilon |
Badis et al., Science 2009 |
|
|
| Tcfe2a |
P15806 |
HLH |
Mus musculus |
transcription factor E2a |
Badis et al., Science 2009 |
|
|
| Tea1 |
P47988 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Ty1 enhancer activator required for full levels of Ty enhancer-mediated transcription; C6 zinc cluster DNA-binding protein |
Zhu et al., GR 2009 |
|
|
| Tec1 |
P18412 |
TEA |
Saccharomyces cerevisiae |
Transcription factor required for full Ty1 epxression, Ty1-mediated gene activation, and haploid invasive and diploid pseudohyphal growth; TEA/ATTS DNA-binding domain family member |
Zhu et al., GR 2009 |
|
|
| Tgif1 |
|
Homeo |
Mus musculus |
TGFB-induced factor 2 |
Berger et al., Cell 2008 |
|
|
| Tgif2 |
Q8C0Y1 |
Homeo |
Mus musculus |
TGFB-induced factor 2 |
Berger et al., Cell 2008 |
|
|
| Titf1 |
P50220 |
Homeo |
Mus musculus |
thyroid transcription factor 1 |
Berger et al., Cell 2008 |
|
|
| Tlx2 |
Q61663 |
Homeo |
Mus musculus |
T-cell leukemia, homeobox 2 |
Berger et al., Cell 2008 |
|
|
| Tye7 |
P33122 |
HLH |
Saccharomyces cerevisiae |
Serine-rich protein that contains a basic-helix-loop-helix (bHLH) DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator |
Zhu et al., GR 2009 |
|
|
| Ume6 |
P39001 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Key transcriptional regulator of early meiotic genes, binds URS1 upstream regulatory sequence, couples metabolic responses to nutritional cues with initiation and progression of meiosis, forms comp... |
Zhu et al., GR 2009 |
|
|
| Uncx4.1 |
Q78DU3 |
Homeo |
Mus musculus |
Unc4.1 homeobox (C. elegans) |
Berger et al., Cell 2008 |
|
|
| Usv1 |
|
Zf_C2H2 |
Saccharomyces cerevisiae |
Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in protein folding, ATP binding, and cell wall biosynthesis |
Zhu et al., GR 2009 |
|
|
| Vax1 |
Q2NKI2 |
Homeo |
Mus musculus |
ventral anterior homeobox containing gene 1 |
Berger et al., Cell 2008 |
|
|
| Vax2 |
Q9WTP9 |
Homeo |
Mus musculus |
ventral anterior homeobox containing gene 2 |
Berger et al., Cell 2008 |
|
|
| Vsx1 |
Q91V10 |
Homeo |
Mus musculus |
visual system homeobox 1 homolog (zebrafish) |
Berger et al., Cell 2008 |
|
|
| Xbp1 |
P40489 |
HTH APSES-type |
Saccharomyces cerevisiae |
Transcriptional repressor that binds to promoter sequences of the cyclin genes, CYS3, and SMF2; expression is induced by stress or starvation during mitosis, and late in meiosis; member of the Swi4... |
Zhu et al., GR 2009 |
|
|
| Yap1 |
P19880 |
bZIP |
Saccharomyces cerevisiae |
Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance; mediates pleiotropic drug and metal resistance; localized to the nucleus in response to the presence of oxi... |
Zhu et al., GR 2009 |
|
|
| Yap6 |
Q03935 |
bZIP |
Saccharomyces cerevisiae |
Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance |
Zhu et al., GR 2009 |
|
|
| Ybr239c |
P38140 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR239C is not an essential gene |
Zhu et al., GR 2009 |
|
|
| Ydr520c |
|
Zn2Cys6 |
Saccharomyces cerevisiae |
Putative transcription factor; contains the (Zn(II)2Cys6 motif; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is viable and sensitive to caffeine |
Zhu et al., GR 2009 |
|
|
| Yer130c |
P39959 |
Zf_C2H2 |
Saccharomyces cerevisiae |
Hypothetical protein |
Zhu et al., GR 2009 |
|
|
| Ygr067c |
P53243 |
Zf_C2H2 |
Saccharomyces cerevisiae |
Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p |
Zhu et al., GR 2009 |
|
|
| Ykl222c |
P35995 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Putative protein of unknown function; similar to transcriptional regulators from the zinc cluster (binuclear cluster) protein family; null mutant is sensitive to caffeine |
Zhu et al., GR 2009 |
|
|
| Yll054c |
|
Zn2Cys6 |
Saccharomyces cerevisiae |
Putative protein of unknown function with similarity to Pip2p, an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene |
Zhu et al., GR 2009 |
|
|
| Yml081w |
Q04545 |
Zf_C2H2 |
Saccharomyces cerevisiae |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YML081w is not an essential gene |
Zhu et al., GR 2009 |
|
|
| Ynr063w |
P53749 |
Zn2Cys6 |
Saccharomyces cerevisiae |
Putative zinc-cluster protein of unknown function |
Zhu et al., GR 2009 |
|
|
| Yox1 |
P34161 |
Homeo |
Saccharomyces cerevisiae |
Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycl... |
Zhu et al., GR 2009 |
|
|
| Ypr013c |
|
Zf_C2H2 |
Saccharomyces cerevisiae |
Putative zinc finger protein; YPR013C is not an essential gene |
Zhu et al., GR 2009 |
|
|
| Ypr015c |
|
Zf_C2H2 |
Saccharomyces cerevisiae |
Hypothetical protein |
Zhu et al., GR 2009 |
|
|
| Ypr196w |
|
Zn2Cys6 |
Saccharomyces cerevisiae |
nuclear protein (putative) |
Zhu et al., GR 2009 |
|
|
| Yrm1 |
|
Zn2Cys6 |
Saccharomyces cerevisiae |
Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes |
Zhu et al., GR 2009 |
|
|
| Yrr1 |
|
Zn2Cys6 |
Saccharomyces cerevisiae |
Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes |
Zhu et al., GR 2009 |
|
|
| Zbtb12 |
Q6P6L4 |
ZnF_C2H2 |
Mus musculus |
zinc finger and BTB domain containing 12: Mus musculus zinc finger and BTB domain containing 12 |
Badis et al., Science 2009 |
|
|
| Zbtb3 |
Q91X45 |
ZnF_C2H2 |
Mus musculus |
zinc finger and BTB domain containing 3: Mus musculus RIKEN cDNA 4930563M09 gene (4930563M09Rik), mRNA |
Badis et al., Science 2009 |
|
|
| Zbtb7b |
Q64321 |
ZnF_C2H2 |
Mus musculus |
Vzinc finger and BTB domain containing 7B: Mus musculus hypothetical gene supported by NM_009565 |
Badis et al., Science 2009 |
|
|
| Zfp105 |
Q3UHV1 |
ZnF_C2H2 |
Mus musculus |
zinc finger protein 105: Mus musculus zinc finger protein 105 (Zfp105) |
Badis et al., Science 2009 |
|
|
| Zfp128 |
Q52KP6 |
ZnF_C2H2 |
Mus musculus |
zinc finger protein 128: Zinc finger protein 128 [Mus musculus] |
Badis et al., Science 2009 |
|
|
| Zfp161 |
Q08376 |
ZnF_C2H2 |
Mus musculus |
zinc finger protein 161: Mus musculus zinc finger protein 161 |
Badis et al., Science 2009 |
|
|
| Zfp187 |
Q5RJ54 |
ZnF_C2H2 |
Mus musculus |
zinc finger protein 187: Mus musculus zinc finger protein 187 |
Badis et al., Science 2009 |
|
|
| Zfp281 |
Q99LI5 |
ZnF_C2H2 |
Mus musculus |
Zinc finger protein 281: Mus musculus zinc finger protein 281, mRNA |
Badis et al., Science 2009 |
|
|
| Zfp410 |
Q8BKX7 |
ZnF_C2H2 |
Mus musculus |
zinc finger protein 410: Mus musculus HCM3688 gene, VIRTUAL TRANSCRIPT, partial sequence, genomic survey sequence |
Badis et al., Science 2009 |
|
|
| Zfp691 |
Q3TDE8 |
ZnF_C2H2 |
Mus musculus |
Zinc finger protein 691: Mus musculus similar to hypothetical protein LOC51058 (LOC242652), mRNA |
Badis et al., Science 2009 |
|
|
| Zfp740 |
Q6NZQ6 |
ZnF_C2H2 |
Mus musculus |
Zinc finger protein 740 |
Badis et al., Science 2009 |
|
|
| Zic1 |
P46684 |
ZnF_C2H2 |
Mus musculus |
Zinc finger protein of the cerebellum 1: Mus musculus similar to zic protein member 1 (Zic1), mRNA |
Badis et al., Science 2009 |
|
|
| Zic2 |
Q62520 |
ZnF_C2H2 |
Mus musculus |
Zic finger protein of the cerebellum 2: Mus musculus Zic finger protein of the cerebellum 2 (Zic2) |
Badis et al., Science 2009 |
|
|
| Zic3 |
Q62521 |
ZnF_C2H2 |
Mus musculus |
zinc finger protein of the cerebellum 3: Mus musculus zinc finger protein of the cerebellum 3, mRNA (cDNA clone IMAGE:30112694), partial cds |
Badis et al., Science 2009 |
|
|
| Zif268 |
P08046 |
ZnF_C2H2 |
Mus musculus |
Transcription factor Zif268 |
Berger et al., Nat Biotech 2006 |
|
|
| Zscan4 |
|
ZnF_C2H2 |
Mus musculus |
zinc finger and SCAN domain containing 4: Mus musculus BAC clone RP23-35L23 from chromosome 7, complete sequence. |
Badis et al., Science 2009 |
|
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